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(dextro/levo-amphetamine) administration is unknown. However, it is understood that Adderall alters the influx of calcium ions at NMDA receptor sites, which in turn affects synaptic plasticity. It should be speculated that synapses reorganize, shift significantly away from homeostasis, and ultimately contribute to Adderall tolerance. Transporter decreases: Research speculates that dopamine transporters (DATs) are altered and/or depleted with repeated Adderall administration. Some sources estimate that following chronic amphetamine administration, dopamine transporters are decreased by up to 40%. Although a 40% depletion is unlikely among those taking medically-approved Adderall dosages, even depletion to a lesser extent may be partially responsible for tolerance onset. What Is Irritable Bowel Syndrome and How Best to Treat It? 22 year old female with ADHD. I& 39;ve been taking Focalin XR (15mg 1x a day) for about 2 weeks but discontinued. Helped significantly with focus and working memory, concentration, and being generally better in all aspects of life. Side effects were minimal except I noticed a rapid heart rate that contributed to being generally anxious. I highly suggest trying it out but be aware of physical side effects. white pill with 377 on it. This medical content is reliable and evidence-based. It was written based on peer-reviewed medical research, reviewed by medical and/or clinical experts, and provides objective information on the disease and treatment of addiction (substance use disorders). Sources listed for reference. Why Some Doctors Are Concerned, and What the FDA Decided to Do About It. 5 Ways to Talk with Young Adults About Alcohol and Drugs. The National Institute on Drug Abuse, NIDA, classifies ketamine as a dissociative drug similar to hallucinogens. NIDA states that the reason people take dissociative drugs is to ?nable them to enter into what they perceive as a more enlightened sense of thinking or being (NIDA). Additionally, from NIDA, ?etamine?lso known as K, Special K, or cat Valium?s a dissociative currently used as an anesthetic for humans as well as animals. Much of the ketamine

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